Publications

CaptureA Mouse Model of Multi-Drug Resistant Staphylococcus aureus-induced Ocular Disease.

Broekema NM, Larsen IV, Naruzawa ES, Filutowicz M, Kolb AW, Teixeira LB, Brandt CR.  A Mouse Model of Multi-Drug Resistant Staphylococcus aureus-induced Ocular Disease.  J Ocul Biol. 2016 Nov;4(2). doi: 10.13188/2334-2838.1000026.


Mapping Murine Corneal Neovascularization and Weight Loss Virulence Determinants in the HSV-1 Genome and the Detection of an Epistatic Interaction between the UL and IRS/US Regions.

Lee K, Kolb AW, Larsen IV, Craven M, Brandt CR.  Mapping Murine Corneal Neovascularization and Weight Loss Virulence Determinants in the HSV-1 Genome and the Detection of an Epistatic Interaction between the UL and IRS/US Regions. J Vir. 2016 Jul 6. pii: JVI.00821-16. [Epub ahead of print]


Primate neural retina upregulates IL-6 and IL-10 in response to a herpes simplex vector suggesting the presence of a pro-/anti-inflammatory axis.

Sauter MM, Brandt CR. Primate neural retina upregulates IL-6 and IL-10 in response to a herpes simplex vector suggesting the presence of a pro-/anti-inflammatory axis.  Exp Eye Res. 2016 May 8. pii: S0014-4835(16)30106-3. doi: 10.1016/j.exer.2016.05.003. [Epub ahead of print]


Both CD8+ and CD4+ T-Cells Contribute to Corneal Clouding and Viral Clearance Following Vaccinia Virus Infection in C57BL/6 Mice

Larsen IV, Clausius H, Kolb AW, Brandt CR.  Both CD8+ and CD4+ T-Cells Contribute to Corneal Clouding and Viral Clearance Following Vaccinia Virus Infection in C57BL/6 Mice. J Virol. 2016. J Virol. 2016 May 11. pii: JVI.00570-16. [Epub ahead of print]


Quantitative Trait Locus Based Virulence Determinant Mapping of the HSV-1 Genome in Murine Ocular Infection: Genes Involved in Viral Regulatory and Innate Immune Networks Contribute to Virulence.

Kolb AW, Lee K, Larsen I, Craven M, Brandt CR. Quantitative Trait Locus Based Virulence Determinant Mapping of the HSV-1 Genome in Murine Ocular Infection:  Genes Involved in Viral Regulatory and Innate Immune Networks Contribute to Virulence. PLoS Pathog. 2016 Mar 10;12(3):e1005499. doi: 10.1371


Recombination Analysis of Herpes Simplex Virus Type 1 Reveals a Bias towards GC Content and the Inverted Repeat Regions.

Lee K, Kolb AW, Sverchkov Y, Cuellar JA, Craven M, Brandt CR.  Recombination Analysis of Herpes Simplex Virus Type 1 Reveals a Bias towards GC Content and the Inverted Repeat Regions.  J Virol. 2015 Apr 29. pii: JVI.00880-15.


Genomic, phylogenetic, and recombinational characterization of herpes simplex virus 2 strains.

Kolb AW, Larsen IV, Cuellar JA, Brandt CR.  Genomic, phylogenetic, and recombinational characterization of herpes simplex virus 2 strains. J Virol. 2015 Jun 15;89(12):6427-34. doi: 10.1128/JVI.00416-15. Epub 2015 Apr 8.


Viral Vector Effects on Exoenzyme C3 Transferase Mediated Actin Disruption and on Outflow Facility.

Slauson SR, Peters DM, Schwinn MK, Kaufman PL, Gabelt BT, Brandt CR.  Viral Vector Effects on Exoenzyme C3 Transferase Mediated Actin Disruption and on Outflow Facility.  Invest Ophthalmol Vis Sci. 2015 Mar 17. pii: IOVS-14-15909. doi: 10.1167/iovs.14-15909. [Epub ahead of print]


Oligonucleotides designed to inhibit TLR9 block Herpes simplex virus type 1 infection at multiple steps

Sauter, M. M., J. J. Gauger, and C. R. Brandt. 2014. Oligonucleotides designed to inhibit TLR9 block Herpes simplex virus type 1 infection at multiple steps. Antiviral Research 109:83-96.


Using HSV-1 Genome Phylogenetics to Track Past Human Migrations

Kolb AW, Ané C, Brandt CR (2013) Using HSV-1 Genome Phylogenetics to Track Past Human Migrations. PLoS ONE 8(10): e76267. doi: 10.1371/journal.pone.0076267


In vivo anti-HSV activity of a sulfated derivative of agaricus brasiliensis mycelia polysaccharide

Cardozo, F. T., I. V. Larsen, E. V. Carballo, G. Jose, R. Stern, R. C. Brummel, C. M. Camelini, M. J. Rossi, C. M. Simões, and C. R. Brandt. 2013. In vivo anti-HSV activity of a sulfated derivative of agaricus brasiliensis mycelia polysaccharide. Antimicrobial Agents and Chemotherapy 57:2541-2549.


Antiviral activity of the EB peptide against zoonotic poxviruses

Altmann, S. E., C. R. Brandt, P. B. Jahrling, and J. E. Blaney. 2012. Antiviral activity of the EB peptide against zoonotic poxviruses. Virology Journal 9:6.


Multiplex sequencing of seven ocular herpes simplex virus type-1 genomes:  Phylogeny, sequence variability and SNP distribution

Kolb, A. W., M. Adams, E. L. Cabot, M. Craven, and C. R. Brandt. 2011. Multiplex sequencing of seven ocular Herpes simplex virus Type-1 genomes:  Phylogeny, sequence variability and SNP distribution. Investigative Ophthalmology and Visual Science 52:9061-9073.


Sequence variation and phosphorylation sites in the herpes simplex virus US1 ocular virulence determinant

Kolb, A. W., T. R. Schmidt, D. W. Dyer, and C. R. Brandt. 2011. Sequence variation and phosphorylation sites in the herpes simplex virus US1 ocular virulence determinant. Investigative Ophthalmology and Visual Science 52:4630-4638.


A quantitative rabbit model of vaccinia keratitis

Altmann, S., A. Emanuel, M. Toomey, K. McIntyre, J. Covert, R. R. Dubielzig, G. Leatherberry, C. J. Murphy, S. Kodihalli, and C. R. Brandt. 2010. A quantitative rabbit model of vaccinia keratitis. Investigative ophthalmology & visual science 51:4531-4540.

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